What are the key findings and do they follow from the data and the authors’ analysis;what is the main message of the study?

Critical Appraisal

Read and critically appraise the chosen paper:

Use of metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind, placebo-controlled trial
Cluver et al., BMJ 2021;374:n2103
https://doi.org/10.1136/bmj.n2103

PART 1: 35% weighting – max 300 words
List 8 points (strengths and weaknesses) about the paper
AND for each point state whether it is a strength or a weakness AND explain why you think this is the case
It is 8 points in total with at least 3 strengths and 3 weaknesses (with a maximum total number of 8 relevant points (strengths and weaknesses combined))

PART 2 – 55% weighting – max 500 words

Write a commentary summarising the study in narrative form (not bullet points)
The commentary should use the following subheadings;
Context of the study
Summary of methods (describe them; no appraisal)
Findings
Conclusions and are they justified?
Implications for practice

References (if used)

When writing your commentary please use the following subheadings:

Context: the place of this study in relation to our current understanding of the topic; what is the background to the study?

Methods: Briefly describe what the study involved, and the methods used in the research. No appraisal of the methods is required in this section, as this is covered in Part 1.

Findings: What are the key findings and do they follow from the data and the authors’ analysis;what is the main message of the study?

Conclusions: Are the conclusions justified?